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What is Immune System

Immune system in our body plays important role to understand: 

• How virus is affecting our body
• How natural antibodies plays important role against virus and
• How the vaccine induced antibodies have role against these viruses.

Immune system works as a defence mechanism against foreign substances like virus, bacteria etc. It provides two types of immunity i.e. Innate Immunity and Adaptive Immunity. 

Innate immunity- It is a born immunity, which fights off the germs before its start getting active. It does not remember for future attack of the same particles.

Adaptive Immunity- The response in this immunity is specific to the germs presented. It involves different cells to fight of the germs. It has a memory inbuilt and remember the pathogen attacked. Second time infection with the same organism will be recognised and destroyed immediately. Vaccination utilise the mechanism of adaptive Immunity.

What role Antibodies play in the Immune System

The immune system defends our body from foreign invaders by using many different cells like B lymphocyte and T lymphocyte. These cells plays an important role in destroying the foreign substances. When the body is attacked by foreign particles, B-lymphocyte triggered and produce antibodies. Antibodies are the proteins to fight viruses and infections. The particles have specific marker called as antigen, against which immune system produce specific antibodies, which attack and kill these particles. Antibodies also remains in the blood circulation, to protect us if later attacked from the same particles. This antibodies are known as natural antibodies. 

In the same way vaccination also works, as it introduce in the body, body recognise it as foreign particles and produce antibodies. Although this does not harm the body. The antibodies works differently depends upon the particles enters into the body i.e. either naturally like virus etc. or through vaccination.

Natural and Specific Antibodies- How it works against Covid-19

Natural antibodies-  These are the antibodies produced when a foreign particle or germs invade a body. As per Dr. G.Vanden Bossche, Veterinary doctor, these antibodies have high broad spectrum and low affinity, provide high protection and are variant non-specific i.e. doesn’t matter what type of coronavirus attacking in the body unless these antibodies are suppressed by other immune response or by specific antibodies. The protection against coronavirus or any of its strain is same and thus provide high protection to the body. 

Specific antibodies or vaccine induced antibodies- These are vaccine induced antibodies or specific antibodies, are long live antibodies, produces strong, long term adaptive immune response and are trained for specific virus. As per Dr. G.Vanden Bossche, when the body invades by the virus, this attack only the antibody specific virus. But when the body is induced by the virus strain eg Covid-19 strain, antibodies does not recognise the strains, which ease them to enter the body and cause disease. These antibodies also suppresses the natural antibodies as they are bigger and stronger, thus allows to move into body and cause deadly effect in the body. 

Are Covid-19 vaccination Safe-Risk and benefits

As per  G.Vanden Bossche, the natural antibodies are suppressed by specific antibodies, thus loosing innate immune system which is a natural immunity, the antibodies produced in this are non-specific and fight against many virus and it strains. He also noted that vaccination is horrifying and reducing natural immunity. 

Though vaccines are considered to be safe by many higher medical authorities. As Covid-19 pandemic are affecting millions, it has been advised to go for vaccination. As per CDC, Vaccine development are being carefully evaluated in the clinical trials and protect people from getting worse symptoms of Covid-19 and may reduce the spreads of infection too. Getting Covid-19 vaccine may offer some natural immunity also and reduce the risk of severe illness as reported. 

As per the expert, both natural immunity and specific immunity produced by a vaccine are important parts of COVID-19 disease. They also trying to provide more updates about it, as the evidences will be available.